Protein Characterization

• High performance liquid chromatography
• PAGE (polyacrylarmide Gel Electrophesis)
• LC Mass Spectrometry
• Immuno Blotting
• Peptide Mapping
• UV scanning • Assay Development

 


In our state-of-the-art cGMP facility outside of Indianapolis we have the capability to purify, fully characterize proteins as reagents and to produce clinical trial material.



Protein Purification (microgram to gram)

• Purification of tissue proteins
• Purification of biosynthetic proteins
• HPLC purification
• Chromatography–afinity, ion exchange, hydrophobic interaction, and size exclusion purification
• Protein refolding
• We specialize in purification of active proteins

 
         
 



 

Process Scale-UP (microgram to gram)




• Scale-up of existing purification process
• Development of new purification processes
• Production of proteins for clinical trials
• Fermentation systems from 10L to 100L
• Lyophilization
• Clean room environments from Class 100,000 to class 100
• Complete range of QC testing capabilities
• Manufacturing areas dedicated to a single product during inoculum, fermentation recovery and purification processes.

 



 

 

 

 

 



Protein Characterization

• High performance liquid chromatography
• PAGE (Polyacrylamide Gel Electrophoresis)
• LC Mass Spectrometry • Immunoblotting
• Peptide Mapping • UV scanning
• Assay Development

Cell Culture (microgram to gram)
• E. coli
• Mammalian Cell


 
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